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Technical Challenges of Real-Time Adaptive MR-Guided Radiotherapy
Daniela Thorwarth1, Daniel A Low2
1Section for Biomedical Physics, Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Frontiers in Oncology
|March 25, 2021
Summary
Hybrid magnetic resonance (MR) imaging and linear accelerator machines offer real-time adaptive radiotherapy (RT). Technical challenges in MR-guided RT must be addressed for safe and effective cancer treatment delivery.
Area of Science:
- Medical Physics
- Radiotherapy Technology
- Medical Imaging
Background:
- Radiotherapy (RT) has advanced with hybrid machines integrating magnetic resonance (MR) imaging and linear accelerators.
- This innovation enables MR-guided cancer treatment, offering high-resolution, real-time imaging capabilities.
Purpose of the Study:
- To discuss the technical challenges hindering safe and robust real-time adaptive MR-guided RT delivery.
- To explore the potential and limitations of MR-based RT workflows.
- To highlight future directions in quantitative MR imaging for biological RT adaptation.
Main Methods:
- Review of technical challenges in MR-guided RT.
- Discussion of magnetic field strength tradeoffs.
- Summary of real-time 3D MR imaging status and potential.
Main Results:
- Hybrid MR-guided RT offers revolutionary potential for adaptive RT.
- Several technical challenges require solutions for reliable implementation.
- Quantitative MR imaging shows promise for future biological adaptation.
Conclusions:
- MR-guided RT is a significant technological advancement in cancer treatment.
- Addressing technical challenges is crucial for realizing the full potential of adaptive RT.
- Future developments in quantitative MR imaging could enable more personalized biological RT adaptation.
