Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.0K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.0K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

808
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
808
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

934
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
934

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence, risk factors, and patient characteristics in severe contact lens-related microbial keratitis.

Acta ophthalmologica·2024
Same author

Psychometric testing of the Norwegian version of the Simulation Design Scale, the Educational Practices Questionnaire and the Student Satisfaction and Self-Confidence in Learning Scale in nursing education.

International journal of nursing studies advances·2024
Same author

Nurse Anesthetist Practice Over 40 Years: A Repeated Cross-Sectional Study in Norway.

AANA journal·2023
Same author

Different pathways for preterm birth between singleton and twin pregnancies: a population-based registry study of 481 176 nulliparous women.

BJOG : an international journal of obstetrics and gynaecology·2022
Same author

The Oslo Ischaemia Study: cohort profile.

BMJ open·2021
Same author

Mapping Schistosoma haematobium for Novel Interventions against Female Genital Schistosomiasis and Associated HIV Risk in KwaZulu-Natal, South Africa.

The American journal of tropical medicine and hygiene·2021

Related Experiment Video

Updated: Nov 11, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.6K

Significant lifespan difference between primary open-angle glaucoma and pseudoexfoliation glaucoma.

Jon Klokk Slettedal1,2, Leiv Sandvik3, Amund Ringvold1,2

  • 1Institute of Clinical Medicine, University of Oslo, Norway.

Heliyon
|March 25, 2021
PubMed
Summary
This summary is machine-generated.

Primary open-angle glaucoma (POAG) is linked to a shorter lifespan, particularly due to cardiovascular disease and cancer. Pseudoexfoliation glaucoma (PEG) does not show this reduced lifespan, highlighting distinct disease differences.

Keywords:
LifespanPrimary open-angle glaucomaPseudoexfoliation glaucomaPseudoexfoliation syndromeSystemic diseases

More Related Videos

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

9.6K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.9K

Related Experiment Videos

Last Updated: Nov 11, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.6K
Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

9.6K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.9K

Area of Science:

  • Ophthalmology
  • Public Health
  • Genetics

Background:

  • Open-angle glaucoma (OAG) encompasses primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEG).
  • Emerging evidence suggests systemic implications for both POAG and PEG.
  • Understanding these systemic effects is crucial for comprehensive patient care.

Purpose of the Study:

  • To investigate the influence of POAG, pseudoexfoliation syndrome (PES), and PEG on lifespan and causes of death.
  • To differentiate the systemic impact of POAG and PEG.

Main Methods:

  • A cohort of 1864 individuals examined in 1985-86 was followed until death (up to 30 years).
  • Data on PES, glaucoma, and cause of death (cardiovascular, cerebrovascular, neoplasms) were collected from the National Death Registry.
  • Statistical analysis compared lifespan across different glaucoma subgroups and the general population.

Main Results:

  • No significant lifespan difference was found for OAG (POAG + PEG) compared to the general population.
  • POAG patients exhibited a reduced lifespan in the cardiovascular death group (2.44 years, p=0.043) after adjusting for gender and age.
  • A significant lifespan difference of 6.87 years (p=0.017) was observed between POAG and PEG in the neoplastic death group.

Conclusions:

  • POAG is associated with reduced lifespan due to neoplasia and cardiovascular disease.
  • Individuals with PES and PEG did not demonstrate similar lifespan reductions.
  • POAG and PEG represent distinct disease entities with differing ocular and systemic characteristics.