Intra-fourth-ventricular choroid plexus papilloma miming ependymoma

Choroid plexus papilloma (CPP), a low incidence central nervous system (CNS) tumor, typically develops as an intraventricular neoplasm arising from the epithelium of the choroid plexus. Infratentorial CPP is predominantly clustered in adults with roughly 70% in the fourth ventricle, while supratentorial CPP commonly found in the lateral ventricles, is the most frequent location in children. The clinical and imaging features of CPP are not typical and may induce the misdiagnosis as other types of primary brain tumors. In this paper, we described a fourth-ventricular CPP that was misdiagnosed as ependymoma despite the manipulation of groundbreaking magnetic resonance imaging (MRI) sequences. These findings indicated that CPP should be considered when performing the differential diagnosis of intraventricular neoplasms.