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Updated: Nov 11, 2025

Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows
Published on: April 25, 2013
Blood Flow Velocimetry in a Microchannel During Coagulation Using Particle Image Velocimetry and Wavelet-Based
E Kucukal1, Y Man1, Umut A Gurkan2
1Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.
Abstract:
This article describes novel measurements of the velocity of whole blood flow in a microchannel during coagulation. The blood is imaged volumetrically using a simple optical setup involving a white light source and a microscope camera. The images are processed using particle image velocimetry (PIV) and wavelet-based optical flow velocimetry (wOFV), both of which use images of individual blood cells as flow tracers. Measurements of several clinically relevant parameters such as the clotting time, decay rate, and blockage ratio are computed. The high-resolution wOFV results yield highly detailed information regarding thrombus formation and corresponding flow evolution that is the first of its kind.

