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[31-P-spectroscopy as a method for studying biochemical changes in skin tumors: exemplified by malignant melanoma and
I C Kiricuta1, W G Schmitt, H K Beyer
1Klinik für Radiologie des Kath, Marienhospitals Herne, Ruhr-Universität Bochum.
Zeitschrift Fur Hautkrankheiten
|February 15, 1988
Abstract:
We report on the basic principles concerning in vivo P-31 MR spectroscopy and give a short review of the corresponding studies on skin tumors described in the literature. Malignant melanoma and squamous cell carcinoma are both characterized by high concentrations of phosphomonoester and phosphodiester. By means of the P-31 spectroscopy technique, we are able to detect changes regarding the tumor metabolism as a response to chemotherapy, irradiation, or biological immune modifiers (e.g. interferon).