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Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension: A
Sajad Khiali1, Naser Khezerlo-Aghdam2, Hossein Namdar2
1Department of Clinical Pharmacy, Drug Applied Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
Pharmacist-directed home blood pressure monitoring (HBPM) and usual care showed no significant difference in decreasing blood pressure. Both methods effectively lowered systolic and diastolic blood pressure in patients with uncontrolled hypertension.
Area of Science:
- Cardiology
- Clinical Pharmacy
- Hypertension Management
Background:
- Pharmacist-led health services are crucial for effective hypertension management.
- Home blood pressure monitoring (HBPM) is a key component in controlling blood pressure.
Purpose of the Study:
- To compare the efficacy of pharmacist-directed home blood pressure monitoring (HBPM) against usual care in patients with uncontrolled hypertension.
- To evaluate blood pressure changes over a six-month period in both intervention and control groups.
Main Methods:
- A randomized controlled trial involving 126 patients with uncontrolled blood pressure.
- Patients were randomized 1:1 to either pharmacist-directed HBPM or usual care.
- The intervention group received training on BP measurement and medication adjustment under pharmacist supervision.
Main Results:
- Both groups showed significant reductions in systolic and diastolic blood pressure by month one, with no significant difference between them.
- This trend of similar blood pressure reduction continued through the six-month study period.
- At six months, both groups achieved comparable blood pressure levels, indicating similar effectiveness.
Conclusions:
- Pharmacist-directed HBPM did not demonstrate a significant advantage over usual care in reducing blood pressure in this patient cohort.
- Both intervention and usual care strategies were effective in managing hypertension.
- Further research may explore long-term outcomes or specific patient subgroups.
Introduction:
Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension.
Aim:
We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care.
Methods:
A total of 126 patients with uncontrolled blood pressure (BP) were randomized 1:1 into the pharmacist-directed HBPM and the usual care groups. In the intervention group, the patients were trained to measure their BPs and adjust their medications based on the designed protocol under the supervision of a clinical pharmacist. The primary endpoint of the study was the comparison of the BPs at baseline and months 1, 3, and 6.
Results:
One month after the allocation, the baseline systolic BP (SBP) (150.5 ± 13.1 vs. 149.7 ± 11.2 mm Hg; P = 0.71) and diastolic BP (DBP) (97.2 ± 9.8 vs. 93.6 ± 14.5; P = 0.11) significantly dropped to the control range equally in 85.2% of the patients in two groups (SBP: 128.8 ± 6.4 vs. 125.6 ± 7.1 mm Hg; P = 0.01 and DBP: 89.1 ± 6.2 vs. 81.5 ± 6.0 mm Hg; P = 0.01). This pattern continued during the study period (month 6; SBP: 115.6 ± 10.1vs. 116.1 ± 9.6 mm Hg; P = 0.78; DBP: 79.0 ± 5.0 vs. 77.2 ± 5.8 mm Hg; P = 0.08).
Conclusions:
In this study, we did not observe any significant difference between the pharmacist-directed HBPM and usual care methods in decreasing BP.
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