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Updated: Nov 11, 2025

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection
Published on: July 28, 2023
The Urea Breath Test for the Noninvasive Detection of Helicobacter pylori
1Department of Gastroenterology, Tallaght University Hospital, Dublin 24, Ireland. Anthony.OConnor@tuh.ie.
Abstract:
The concept of the urea breath test (UBT), as a method for H. pylori detection, is based on the ability of the H. pylori urease enzyme to break down an isotope-labelled urea solution ingested by the patient into carbon dioxide (CO2) and ammonia. This chapter summarizes the current use of the UBT and the utility of the "UBT and Treat" strategy compared to other strategies for the management of H. pylori infection . Different UBT methods are described as well as factors affecting the accuracy of the test.
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