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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
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Fluorescence-guided cancer surgery-A new paradigm.
Subramanyeshwar Rao Thammineedi1, Ajesh Raj Saksena2, Syed Nusrath3
1Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.
Journal of Surgical Oncology
|March 25, 2021
Summary
Fluorescence-guided surgery (FGS) enhances oncosurgery by aiding tumor identification, perfusion assessment, and lymph node mapping. This review covers FGS principles, dyes, platforms, and applications, focusing on abdomino-thoracic malignancies.
Area of Science:
- Surgical Oncology
- Medical Imaging
- Biotechnology
Background:
- Fluorescence-guided surgery (FGS) is an innovative technique enhancing surgical procedures.
- It assists surgeons in critical aspects of oncosurgery, including tumor visualization and nodal assessment.
Purpose of the Study:
- To provide a comprehensive overview of FGS principles, available agents, and platforms.
- To summarize the current literature on FGS utility, particularly in abdomino-thoracic malignancies.
Main Methods:
- Literature review of fluorescence-guided surgery applications.
- Focus on principles, dyes, platforms, and surgical utility in oncology.
Main Results:
- FGS offers versatile applications in oncosurgery.
- The review highlights its role in perfusion assessment, tumor/metastasis identification, and lymph node/leak mapping.
Conclusions:
- Fluorescence-guided surgery is a promising adjunct for oncosurgery.
- Its application in abdomino-thoracic malignancies warrants further investigation and adoption.

