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Differentiation of serologically related serogroups of Legionella pneumophila
1Institute of Epidemiology, Medical Faculty of the Comenius University, Bratislava, Czechoslovakia.
Abstract:
Immune sera of different laboratory animals were studied in comparative tests for their differentiating ability in respect of closely related serogroups of Legionella pneumophila. Strains of serogroups 3 and 6, not distinguishable using rabbit sera, were found to be easily differentiated by mouse immune sera. Guinea pig and hamster sera revealed a lower differentiating ability. Concerning the differentiation of serogroups 5 and 8 none of the tested animals produced group-specific antibodies only. The typical coagglutination of serogroup 4 found regularly in rabbit immune sera against serogroup 8, in contrast to serogroup 5 sera, can be considered as an additional indicator to be used for differentiation of the two serogroups.