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Published on: November 16, 2017
Olanexidine gluconate formulations as environmental disinfectants for enveloped viruses infection control
K Imai1, A Hagi2, S Yamagawa2
1Naruto Research Institute, Research and Development Center, Otsuka Pharmaceutical Factory, Inc., Tokushima, Japan; Department of Frontier Science for Advanced Environment, Graduate School of Environmental Studies, Tohoku University, Miyagi, Japan.
Abstract:
This study investigated the potential of olanexidine gluconate as environmental disinfectant against enveloped viruses in the suspension test and three non-porous surface tests. In the suspension test, olanexidine gluconate showed immediate virucidal activity. In addition, non-porous surface tests demonstrated that, although the immediate effect of aqueous formulations was weak, the final virucidal efficacy outcompeted that of ethanol for disinfection. Furthermore, the effectiveness of olanexidine gluconate persisted even after drying on environmental surfaces. This study demonstrated the potential usage of olanexidine gluconate formulations as an environmental disinfectant in the infection control of enveloped viruses.
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