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Updated: Nov 11, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior"
Dean Hamer1,2, Brian Mustanski3,4, Randall Sell5
1National Cancer Institute, Bethesda, MD 20892, USA. deanhamer@aol.com.
Abstract:
The phenotypic measures used by Ganna et al (Research Articles, 30 August 2019, p. 882) lump together predominantly heterosexual, bisexual, and homosexual individuals, including those who have experimented with a same-sex partner only once. This may have resulted in misleading associations to personality traits unrelated to understood categories of human sexuality. Scientific studies of human sexuality should use validated and reliable measures of sexual behaviors, attractions, and identities that capture the full spectrum of complexity.
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