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Updated: Nov 11, 2025

Author Spotlight: Integrating Biochemical Functions of β-Glucanases and Peroxidase Enzymes in Wheat-RWA Interaction
Published on: July 26, 2024
A Riddle, Wrapped in a Mystery, Inside an Enigma: Another Key to Wheat Sensitivity?
Heather J Galipeau1, Elena F Verdu
1Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Canada .
Abstract:
Nonceliac gluten sensitivity, or the more preferred term, nonceliac wheat sensitivity (NCWS), is a heterogenous condition that is diagnosed purely on the basis of symptoms and without an understanding of disease mechanisms and triggers. Biomarkers to identify patients and implementation of dietary treatment in a personalized manner are needed. Mansueto et al. identified a population of NCWS patients with associated autoimmune markers and immune activation. The presence of these markers could be used, in combination with other serological tests, to help develop better diagnostic strategies for NCWS.
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