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Related Concept Videos

Proofreading01:31

Proofreading

7.5K
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...
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Proofreading01:43

Proofreading

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Overview
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Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

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After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
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Mismatch Repair01:36

Mismatch Repair

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Mismatch Repair01:20

Mismatch Repair

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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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Repressible Operon: trp Operon01:21

Repressible Operon: trp Operon

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The trp operon in Escherichia coli exemplifies a repressible operon. It regulates the synthesis of tryptophan through repressor-mediated transcriptional control and attenuation. This dual regulatory mechanism ensures tryptophan biosynthesis occurs only when needed, conserving cellular resources.Structure of the trp OperonThe trp operon consists of five structural genes (trpE, trpD, trpC, trpB, and trpA) that encode enzymes for tryptophan biosynthesis. These genes are transcribed as a single...
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Related Experiment Video

Updated: Nov 11, 2025

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
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Erratum:

    Evolutionary Applications
    |March 26, 2021
    PubMed
    Summary

    This study corrects a previous article DOI. The corrected DOI is 10.1111/eva.13076. Ensure accurate citation for this research.

    Area of Science:

    • Evolutionary biology
    • Genetics

    Context:

    • Correction of a previously published article DOI.
    • Ensuring accurate referencing in scientific literature.

    Purpose:

    • To provide the correct Digital Object Identifier (DOI) for a scientific publication.
    • To facilitate proper citation and retrieval of research findings.

    Summary:

    • The article DOI: 10.1111/eva.13076 has been corrected.
    • This ensures readers can access the intended research accurately.

    Impact:

    • Improved accuracy in scientific referencing.
    • Enhanced discoverability of the corrected research article.

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