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Clinical characteristics of morning glory disc anomaly in South India

Jayant Kumar1, Olukorede O Adenuga2, Kritika Singh1

  • 1Department of Vitreo- Retina Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India.

Taiwan Journal of Ophthalmology
|March 26, 2021
PubMed
Abstract

Insights

Morning Glory Disc Anomaly (MGDA) patients in India often present late, leading to poor visual outcomes. Early detection and treatment of complications are vital for preserving vision and managing associated systemic conditions.

Area of Science:

  • Ophthalmology
  • Medical Genetics
  • Pediatric Ophthalmology

Background:

  • Morning Glory Disc Anomaly (MGDA) is a rare congenital condition affecting the optic nerve.
  • Previous reports from India primarily consisted of isolated case studies.

Purpose of the Study:

  • To characterize the demographic and clinical features of MGDA patients in South India.
  • To establish a baseline for understanding MGDA prevalence and presentation in the region.

Main Methods:

  • Retrospective analysis of medical records from a tertiary eye hospital.
  • Data collected over an 8-year period.
  • Demographic and clinical data analyzed using Epi Info software.

Main Results:

  • Study included 44 patients (51 eyes); 56.8% males, 43.2% females.
  • Common ocular associations: strabismus, refractive error, retinal detachment.
  • Frequent systemic associations: cleft lip and palate; 51% of eyes presented with blindness.

Conclusions:

  • MGDA patients in India experience delayed presentation and poor visual prognosis.
  • Timely diagnosis and intervention for blinding complications are essential.
  • Associated systemic abnormalities necessitate a multidisciplinary management approach.
Keywords:
Cleft lipIndiamorning glory disc anomalyretinal detachmentstrabismus

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