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Related Experiment Video

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Destination Joint Spacers: A Similar Infection-Relief Rate But Higher Complication Rate Compared with Two-Stage

Yuan-Qing Cai1, Xin-Yu Fang1, Chang-Yu Huang1

  • 1Department of Orthopaedic Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Orthopaedic Surgery
|March 26, 2021
PubMed
Summary
This summary is machine-generated.

Destination joint spacers offer a similar infection-relief rate for periprosthetic joint infection (PJI) patients compared to two-stage revision. However, destination spacers have a higher complication incidence, making them a last resort option for select PJI cases.

Keywords:
ComplicationDestination joint spacerInfection-reliefPeriprosthetic joint infectionTwo-stage revision

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Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Biomaterials Science

Background:

  • Periprosthetic joint infection (PJI) is a serious complication following joint replacement surgery.
  • Management of chronic PJI often involves complex surgical interventions.
  • Two-stage revision and the use of destination joint spacers are established treatment options.

Purpose of the Study:

  • To compare the clinical outcomes of periprosthetic joint infection (PJI) patients treated with a destination joint spacer versus traditional two-stage revision.
  • To evaluate infection-relief rates and complication incidence between the two treatment groups.

Main Methods:

  • Retrospective analysis of 62 chronic PJI patients from January 2006 to December 2017.
  • Diagnosis of PJI based on MSIS criteria.
  • Comparison of infection-relief rates and complications between destination joint spacer (n=21) and two-stage revision (n=41) groups.

Main Results:

  • No significant difference in infection-relief rates between destination joint spacer (14.29% recurrent infection) and two-stage revision (9.76% recurrent infection) groups.
  • Higher incidence of complications, including spacer fractures, dislocations, and deep venous thrombosis, in the destination joint spacer group.
  • Patients receiving destination spacers had a higher Charlson Comorbidity Index.

Conclusions:

  • Destination joint spacers provide comparable infection control to two-stage revision for PJI.
  • The higher complication rate associated with destination spacers suggests their use as a last resort for specific PJI patients.
  • Further research may explore strategies to mitigate complications in destination spacer cases.