Related Experiment Video
Updated: Nov 11, 2025
State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Fetal Trigonocephaly (Strawberry Skull) in Early Pregnancy
Ayala Gover1,2, Nizar Khatib3, Ron Beloosesky3
1Neonatal Intensive Care Unit, Carmel Medical Center, Haifa, Israel.
Abstract:
Trigonocephaly was previously described prenatally in association with severe abnormalities, mostly observed after 18 weeks of gestation. We describe our experience with this finding in early pregnancy, between 14 and 17 weeks of gestation. Our series includes 18 cases of trigonocephaly with several etiologies; trisomy 18, de novo translocation, thanatophoric dysplasia, and open spina bifida without hydrocephalus. Two fetuses had no other significant abnormalities and a spontaneous normalization of the skull shape was observed on follow-up. Both had normal genetic testing and postnatal outcome. These two cases represent a new phenomenon of an isolated transient form with normal outcome.
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