Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

iPS Cell Differentiation01:22

iPS Cell Differentiation

2.9K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.9K
Skin Cancer01:30

Skin Cancer

5.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.1K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.0K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can Systemic Immunomodulatory Therapy Induce Remission of Atopic Dermatitis? A Systematic Review.

Journal of cutaneous medicine and surgery·2026
Same author

Serious infection risk with systemic treatments for psoriasis: A cohort study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

The British journal of dermatology·2026
Same author

Evaluation of a Therapeutic Drug Monitoring Strategy for Adalimumab in Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study.

Clinical and translational science·2026
Same author

Serious infection risk of certolizumab compared with other systemic therapies in women with psoriasis.

The British journal of dermatology·2026
Same author

Genetic proxies of GLP1R expression are associated with lower risk of psoriasis and psoriatic arthritis.

The British journal of dermatology·2026
Same author

The definition of response and inadequate response to topical corticosteroid treatment in atopic dermatitis and related skin inflammatory diseases: A GA<sup>2</sup>LEN ADCARE statement paper.

The World Allergy Organization journal·2026

Related Experiment Video

Updated: Nov 11, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

602

Meeting Report: Psoriasis Stratification to Optimize Relevant Therapy Showcase.

Zenas Z N Yiu1, Jonathan N W N Barker2, Michael R Barnes3

  • 1Centre for Dermatology Research, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom.

The Journal of Investigative Dermatology
|March 27, 2021
PubMed
Summary

Stratified medicine aims to predict psoriasis treatment response using patient data. The Psoriasis Stratification to Optimise Relevant Therapy (PSORT) Consortium is advancing this approach for better biologic therapy selection.

More Related Videos

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.2K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.5K

Related Experiment Videos

Last Updated: Nov 11, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

602
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.2K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.5K

Area of Science:

  • Dermatology and Precision Medicine
  • Translational Research in Psoriasis Management

Background:

  • Psoriasis treatment response prediction is currently uncertain.
  • A stratified medicine approach offers improved clinical decision-making.
  • No established predictive models exist for routine psoriasis treatment selection.

Purpose of the Study:

  • To disseminate research findings from the Psoriasis Stratification to Optimise Relevant Therapy (PSORT) Consortium.
  • To highlight advances in identifying predictors and stratifiers of psoriasis response to biologic therapies.
  • To foster collaboration among stakeholders in stratified medicine for psoriasis.

Main Methods:

  • The PSORT Consortium is an academic-industrial collaboration funded by the UK Medical Research Council.
  • Data integration includes clinical, pharmacological, and -omics information from individual patients.
  • A showcase meeting convened 80 stakeholders to discuss research progress.

Main Results:

  • Significant advances have been made by the PSORT Consortium in identifying potential predictive biomarkers.
  • Research is progressing towards developing a predictive model for psoriasis treatment response.
  • Dissemination of findings aims to accelerate the adoption of stratified medicine.

Conclusions:

  • The PSORT Consortium is making substantial progress towards a stratified medicine approach for psoriasis.
  • Predictive models hold promise for optimizing biologic therapy selection in psoriasis patients.
  • Continued research and collaboration are crucial for clinical implementation.