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Related Concept Videos

Viruses with RNA Genomes01:29

Viruses with RNA Genomes

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RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
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siRNA - Small Interfering RNAs02:30

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Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
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Types of RNA01:20

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Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
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Types of RNA01:23

Types of RNA

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Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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RNA Interference01:23

RNA Interference

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions
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Host-virus interactions mediated by long non-coding RNAs.

Ashish Prasad1, Manoj Prasad1

  • 1National Institute of Plant Genourrent overview ome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India.

Virus Research
|March 27, 2021
PubMed
Summary
This summary is machine-generated.

Long non-coding RNAs regulate interactions between viruses and hosts in plants and animals. These molecules show potential as therapeutic and diagnostic markers for viral diseases.

Keywords:
LincRNALncRNASub-viral RNAsViroidsVirussgRNAs

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Area of Science:

  • Molecular Biology
  • Virology
  • Genomics

Background:

  • Viruses are obligate pathogens impacting global health and economies.
  • Plants and animals possess defense mechanisms against viral infections.
  • Viruses exploit host cell machinery for replication.

Purpose of the Study:

  • To review recent advancements in understanding animal- and plant-virus interactions.
  • To highlight the role of long non-coding RNAs in these interactions.

Main Methods:

  • Literature review of recent studies on viral interactions.
  • Focus on the role of long non-coding RNAs in plant and animal systems.

Main Results:

  • Long non-coding RNAs (lncRNAs) are key regulators of plant-virus and animal-virus interactions.
  • Both pro-viral and anti-viral lncRNAs have been identified.
  • lncRNAs demonstrate potential as diagnostic markers and therapeutic agents.

Conclusions:

  • lncRNAs are crucial players in host-virus dynamics across kingdoms.
  • Further research into lncRNAs could lead to novel antiviral strategies.