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Related Experiment Videos

American Academy of Optometry Microbial Keratitis Think Tank.

Loretta B Szczotka-Flynn, Joseph P Shovlin1, Cristina M Schnider2

  • 1Northeastern Eye Institute, Scranton, Pennsylvania.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|March 27, 2021
PubMed
Summary

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The rate of contact lens-related infections remains unchanged despite innovations. Serious infections from Acanthamoeba and fungi are increasing, particularly in children, necessitating further research and surveillance.

Area of Science:

  • Ophthalmology
  • Microbiology
  • Public Health

Background:

  • Contact lens-associated microbial keratitis (CLAMK) is a significant concern.
  • Recent trends indicate an increase in severe infections, particularly those involving Acanthamoeba and fungi.
  • The growing prevalence of contact lens use in pediatric populations requires focused attention.

Framework:

  • The American Academy of Optometry (AAO) convened a Think Tank in 2019 to address CLAMK.
  • Discussions covered epidemiology, pathogenesis, risk factors, and emerging challenges.
  • Key areas included nonbacterial keratitis, pediatric CLAMK, myopia control, and the ocular microbiome.

Implementation:

  • Microbial keratitis rates have remained static for 30 years, unaffected by new lens technologies.

Related Experiment Videos

  • Silicone hydrogel and daily disposable lenses have not demonstrably altered overall infection rates.
  • Overnight orthokeratology may elevate the risk of Acanthamoeba infections in children.

    • Implications:

    • Patient compliance with lens care remains a critical risk factor.
    • Further research, including case-control studies and registries, is essential.
    • Understanding host microbiome and genetic susceptibility may offer new avenues for prevention and treatment.