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Comparison between externally stented and unstented PTFE vascular grafts
M M Dunn1, D R Robinette, J B Peoples
1Department of Surgery, Wright State University School of Medicine, Dayton, Ohio.
The American Surgeon
|June 1, 1988
Summary
External stenting of polytetrafluoroethylene (PTFE) grafts did not improve patency rates in canine hip joint bypass surgery. Intrinsic graft factors appear more critical than external support for maintaining vascular graft patency.
Area of Science:
- Vascular Surgery
- Biomedical Engineering
- Comparative Pathology
Background:
- External stenting of synthetic vascular grafts is hypothesized to enhance patency, particularly in low-flow conditions or across joints.
- Polytetrafluoroethylene (PTFE) grafts are commonly used in vascular reconstructions.
Purpose of the Study:
- To compare the patency rates of externally stented versus nonstented PTFE vascular grafts placed across the hip joint in a canine model.
Main Methods:
- Bilateral common iliac to common femoral artery bypass was performed in 20 dogs using PTFE grafts.
- Grafts were randomly assigned to receive external stenting or serve as nonstented controls.
- Graft patency was assessed via angiography after 90-120 days.
Main Results:
- Overall graft patency was 65%, with no statistically significant difference between stented and nonstented PTFE grafts.
- 95% of dogs had at least one graft (stented or nonstented) patent or occluded at study completion.
- One graft was removed early due to infection.
Conclusions:
- External graft support does not significantly influence PTFE graft patency in this canine model across the hip joint.
- Intrinsic factors of the vascular graft are likely more critical determinants of long-term patency than external stenting.