Related Experiment Video
Updated: Nov 11, 2025

05:49
Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
Published on: October 10, 2019
6.8K
Variations in Demand across England for the Magnetic Resonance-Linac Technology, Simulated Utilising Local-level
T Mee1, A J Vickers1, R Jena2
1Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Summary
Demand for the new magnetic resonance-linac (MR-linac) cancer treatment varies significantly across England. Local data is crucial for planning MR-linac services due to regional differences in cancer burden.
Area of Science:
- Oncology
- Radiotherapy
- Health Services Research
Background:
- Cancer incidence and treatment demand differ regionally across England.
- The magnetic resonance-linac (MR-linac) is an advanced radiotherapy technology integrating imaging and treatment delivery.
- Accurate demand forecasting is essential for effective healthcare resource allocation.
Purpose of the Study:
- To model the demand for MR-linac services across England at a local level.
- To quantify variations in MR-linac demand based on cancer incidence and population data.
- To assess the impact of using national versus local data for MR-linac service planning.
Main Methods:
- Utilized the Malthus radiotherapy model, incorporating Clinical Commissioning Group (CCG) population and cancer data.
- Simulated MR-linac demand for all CCGs and Radiotherapy Operational Delivery Networks (RODNs) in England.
- Incorporated initial clinical indications from the MR-linac consortium into decision trees.
Main Results:
- MR-linac could potentially service 16% of England's total radiotherapy fraction burden.
- Simulated annual demand varied from 3000 to 10,600 fractions/million population at the CCG level.
- Using national averages for demand prediction led to significant over- or underestimations at the RODN level (up to 8400 fractions).
Conclusions:
- Regional variations in cancer burden necessitate local-level data for planning new cancer technologies like the MR-linac.
- Failure to account for local demand variations can lead to substantial inaccuracies in service planning.
- Accurate, localized demand modeling is critical for optimizing radiotherapy resource allocation and patient access.

