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Updated: Nov 11, 2025

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K
Published on: January 11, 2019
Going Low in a World Going High: The Physiologic Use of Lower Frequency Electron Paramagnetic Resonance
Howard J Halpern1,2, Boris M Epel1,2
1Center for EPR imaging in vivo physiology, University of Chicago.
Abstract:
Yakov Sergeevich Lebedev was a pioneer in high frequency EPR, taking advantage of the separation of g-factor anisotropy effects from nuclear hyperfine splitting and the higher frequency molecular motion sensitivity from higher frequency measurements8. This article celebrates a second EPR subfield in which Prof. Lebedev pioneered, EPR imaging. 9 We celebrate the clinical enhancements that are suggested in this low frequency work and imaging application to animal physiology at lower-than-standard EPR frequencies.
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