Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

2.4K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
2.4K
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

59
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
59
T Cell Types and Functions01:24

T Cell Types and Functions

1.7K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
1.7K
Autoimmune Disorders01:29

Autoimmune Disorders

1.1K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disease-modifying treatment for multiple sclerosis in Poland in a European context: current practices and therapeutic strategies.

Neurologia i neurochirurgia polska·2026
Same author

Aging immunity - the role of T and B cells in neurological disorders among older adults.

Neurologia i neurochirurgia polska·2025
Same author

Cognitive dysfunction and atrophic changes of selected cerebral structures in patients with relapsing-remitting multiple sclerosis.

Postepy psychiatrii neurologii·2025
Same author

The Role of Epstein-Barr Virus in the Pathogenesis of Autoimmune Diseases.

Medicina (Kaunas, Lithuania)·2025
Same author

Update on diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) - recommendations of Section of Multiple Sclerosis and Neuroimmunology of Polish Neurological Society.

Neurologia i neurochirurgia polska·2024
Same author

Selected Interleukins Relevant to Multiple Sclerosis: New Directions, Potential Targets and Therapeutic Perspectives.

International journal of molecular sciences·2024

Related Experiment Video

Updated: Nov 11, 2025

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
09:46

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

Published on: September 21, 2021

5.0K

Multiple sclerosis patients and COVID-19.

Hubert Mado1, Monika Adamczyk-Sowa1

  • 1Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland, 3 Maja Street 13/15, 41-800 Zabrze, Poland.

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
|March 29, 2021
PubMed
Summary
This summary is machine-generated.

Coronavirus disease 2019 (COVID-19) poses risks for multiple sclerosis (MS) patients, especially those on immunosuppressants. This review examines current knowledge on COVID-19 severity in individuals with MS.

Keywords:
COVID-19DMTMSMultiple sclerosisSARS-CoV-2

More Related Videos

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.4K
Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

1.8K

Related Experiment Videos

Last Updated: Nov 11, 2025

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
09:46

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

Published on: September 21, 2021

5.0K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.4K
Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

1.8K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Coronavirus disease 2019 (COVID-19) presents significant global health challenges.
  • Multiple sclerosis (MS) patients often have comorbidities and are treated with immunosuppressive therapies.
  • These factors raise concerns about potential increased COVID-19 severity in the MS population.

Purpose of the Study:

  • To review and synthesize current scientific understanding regarding the severity of COVID-19 in patients diagnosed with multiple sclerosis.
  • To identify key considerations for managing COVID-19 in this specific patient group.

Main Methods:

  • Literature review of existing studies and clinical observations.
  • Analysis of data pertaining to COVID-19 outcomes in multiple sclerosis patients.
  • Synthesis of information on risk factors and disease progression.

Main Results:

  • Data on COVID-19 outcomes in MS patients are still emerging.
  • Immunosuppressive treatments may influence disease course and severity.
  • Further research is needed to fully elucidate the impact of MS and its treatments on COVID-19.

Conclusions:

  • Multiple sclerosis patients may face unique challenges when contracting COVID-19.
  • Understanding the interplay between MS, treatments, and COVID-19 is crucial for clinical practice.
  • Continued research is essential to guide optimal care and mitigate risks.