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Related Experiment Video

Updated: Nov 11, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

Chorioretinal Alterations Induced by Preeclampsia.

Xinyi He^1,2, Yimei Ji³, Meiting Yu²

¹Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.

Journal of Ophthalmology

|March 29, 2021

Summary

Hypertension in pregnancy, a microvascular disease, can cause organ failure. Fundus examination offers a noninvasive method for early diagnosis and risk assessment in preeclampsia.

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Last Updated: Nov 11, 2025

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Retinal Pathophysiological Evaluation in a Rat Model

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Published on: May 6, 2022

Area of Science:

Ophthalmology
Obstetrics
Cardiovascular Medicine

Background:

Hypertension during pregnancy is a serious microvascular disease affecting end-organ circulation.
It can lead to severe complications like kidney, lung, and brain failure.
Preeclampsia management hinges on determining the optimal timing for delivery.

Purpose of the Study:

To summarize common structural fundus changes in preeclampsia patients.
To review the application of quantitative observation for chorioretinal alterations.
To guide treatment strategies using sensitive fundus change detection.

Main Methods:

Systematic observation of the fundus for microcirculatory state assessment.
Comprehensive review of structural changes in blood vessels, choroid, and retina.
Analysis of quantitative observation techniques for chorioretinal alterations.

Main Results:

Fundus examination is a feasible and noninvasive method for preeclampsia assessment.
Identified common structural changes in the fundus associated with pregnancy-induced hypertension.
Highlighted the potential of quantitative fundus analysis for precise monitoring.

Conclusions:

Early diagnosis and treatment of hypertensive disorders in pregnancy are crucial.
Fundus examination aids in assessing microvascular damage and guiding clinical decisions.
Preventing long-term ocular and cardiovascular risks in pregnant women is paramount.