Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

4.4K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
4.4K
Cross-bridge Cycle01:26

Cross-bridge Cycle

120.4K
As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
120.4K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

2.3K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
2.3K
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

124
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
124
Cardiac Output and Stroke Volume01:11

Cardiac Output and Stroke Volume

3.9K
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac...
3.9K
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

3.8K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Training that sticks: sustaining knowledge and communication excellence in geriatric oncology through a multidisciplinary training program.

Innovation in aging·2026
Same author

Pembrolizumab, Temozolomide and HSPPC-96 Vaccine in Newly Diagnosed Glioblastoma Post-Chemoradiation: Results from a Multi-institutional, Phase 2, Randomized, Placebo-Controlled Trial.

medRxiv : the preprint server for health sciences·2026
Same author

Nonsurgical Treatment of Anterior Cruciate Ligament Tears: What Is the Evidence and Who Are the Candidates?

Current sports medicine reports·2026
Same author

Set of Cochrane Overviews of Systematic Reviews Show the Limits of Current Evidence on Health Policy, Systems, and Services Research in Rehabilitation.

American journal of physical medicine & rehabilitation·2026
Same author

Continuous glucose monitoring to support the diagnosis of MODY: A multicenter cross-sectional and prospective study.

Medicina clinica·2026
Same author

Technological Integration in Aesthetic Practice: A Systematic Review of Artificial Intelligence, Augmented Reality and Robotics in Cosmetic Procedures.

Aesthetic plastic surgery·2026

Related Experiment Video

Updated: Nov 11, 2025

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.9K

Stroke and sarcopenia.

Manuel F Mas1, Javier González1, Walter R Frontera1,2

  • 1Department of Physical Medicine, Rehabilitation, and Sports Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.

Current Physical Medicine and Rehabilitation Reports
|March 29, 2021
PubMed
Summary
This summary is machine-generated.

Sarcopenia, a condition of muscle loss, is common in stroke survivors, affecting 14-54% and worsening functional recovery. Early identification and treatment of sarcopenia are crucial for better outcomes post-stroke.

Keywords:
agingcerebrovascular accidentsecondary sarcopeniaskeletal muscle

More Related Videos

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
03:52

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

Published on: February 21, 2025

710
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

861

Related Experiment Videos

Last Updated: Nov 11, 2025

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.9K
The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
03:52

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

Published on: February 21, 2025

710
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

861

Area of Science:

  • Neurology
  • Gerontology
  • Muscle Physiology

Background:

  • Stroke significantly impacts skeletal muscle health.
  • Sarcopenia, age-related muscle loss, is increasingly recognized in older populations.
  • The interplay between stroke and sarcopenia requires further investigation.

Purpose of the Study:

  • To review recent research on skeletal muscle changes post-stroke.
  • To determine the incidence of sarcopenia in stroke survivors.
  • To evaluate the effects of sarcopenia on functional outcomes after stroke.

Main Methods:

  • Systematic review of scientific literature.
  • Analysis of studies focusing on stroke and sarcopenia.
  • Evaluation of reported incidence rates and functional outcomes.

Main Results:

  • Limited recent studies on stroke-related sarcopenia exist, possibly due to evolving definitions.
  • Sarcopenia incidence in stroke patients ranges from 14% to 54%.
  • Pre-existing sarcopenia is linked to poorer recovery and functional outcomes.

Conclusions:

  • Sarcopenia may be more prevalent before a stroke than previously thought.
  • Sarcopenia can significantly impair functional recovery following a stroke.
  • Further large-scale studies are needed to clarify the stroke-sarcopenia relationship and guide clinical practice.