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Updated: Nov 11, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Problematic Purpura
Marina K Ibraheim1, Sheela Gavvala2
1Dermatology, John P. and Kathrine G. McGovern School of Medicine, University of Texas Health Science Center, Houston, USA.
Abstract:
Post-emetic purpura is an often-forgotten cause of facial rash in the acute setting and can often be mistaken for more dangerous etiologies. We present a case of a child recently treated with trimethoprim/sulfamethoxazole for impetigo who demonstrated a new rash after multiple episodes of vomiting. Lab workup, in conjunction with patient history and lesion location, pointed toward a diagnosis of post-emetic purpura. Careful consideration of the history, physical examination findings, location of the lesion, and laboratory findings are essential for diagnosing post-emetic purpura and differentiating it from other etiologies acutely.
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