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Skull hemophilia pseudotumor: A case report.
Kunzhe Lin1, Yong Fan2, Zhehui Lin3
1Department of Neurosurgery, Affiliated Fuzhou First Hospital of Fujian Medical University, No. 190, Dadao Road, Fuzhou 350009, Fujian, China.
Open Medicine (Warsaw, Poland)
|March 29, 2021
Summary
This report details a rare skull hemophilia pseudotumor in a 34-year-old male. Surgical removal with factor VIII therapy proved effective for this skull lesion.
Area of Science:
- Neurosurgery
- Hematology
- Radiology
Background:
- Hemophilia pseudotumors are rare, often presenting as space-occupying lesions.
- Skull involvement is exceptionally uncommon, posing diagnostic and therapeutic challenges.
Observation:
- A 34-year-old male presented with dizziness and a palpable skull bulge.
- Imaging revealed a significant lesion with calcifications in the frontal-temporal-parietal bone.
- MRI demonstrated a large, mixed-signal mass within the skull.
Findings:
- Surgical intervention was performed using neurological navigation for precise resection.
- Intraoperative and postoperative management included clotting factor VIII substitution therapy.
- Complete removal of the skull hemophilia pseudotumor was achieved.
Implications:
- Diagnosis relies on imaging and family history, especially for rare skull presentations.
- Treatment strategies range from conservative management to surgical excision based on lesion impact.
- Perioperative factor VIII supplementation is critical for successful surgical outcomes in hemophilia patients.
