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Respiratory Disorders in Parkinson's Disease
Evelyn M Guilherme1,2, Roberta de Fátima Carreira Moreira2, Adriele de Oliveira1,2
1Laboratory of Neuroscience, Federal University of Sao Carlos, Brazil.
Parkinson disease patients often experience pulmonary dysfunction, reduced respiratory muscle strength, and decreased physical capacity. These respiratory issues worsen as the disease progresses, impacting quality of life.
Area of Science:
- Neurology
- Pulmonology
- Movement Disorders
Background:
- Non-motor symptoms of Parkinson's disease (PD) can manifest early and progress over time.
- Respiratory changes in PD patients can limit physical activity, reducing overall functionality and quality of life.
Approach:
- A systematic review was conducted, searching major databases up to November 2020.
- Nineteen studies evaluating pulmonary function, respiratory muscle strength, and physical capacity in PD patients were selected.
- Studies focused exclusively on Parkinson's disease, excluding patients with other comorbidities.
Key Points:
- Parkinson's disease patients demonstrate a higher prevalence of obstructive or restrictive pulmonary dysfunction compared to healthy individuals.
- Patients with PD exhibit diminished respiratory muscle strength, leading to reduced endurance capacity.
- The severity of respiratory impairment in PD appears to correlate with disease progression.
Conclusions:
- Parkinson's disease is associated with significant respiratory complications, including pulmonary dysfunction and reduced respiratory muscle strength.
- These respiratory deficits contribute to decreased physical capacity and are linked to disease advancement.
- Addressing respiratory health is crucial for managing Parkinson's disease progression and improving patient outcomes.
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