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[Advances in the cytotoxic mechanism of nanomaterials graphene oxide]
1Hangzhou Medical College, Institute of Occupational Diseases, Hangzhou 310013, China.
Abstract:
Graphene oxide is a novel two-dimensional carbon nanomaterial, but it has potential risks for the health of occupationally exposed workers. This article briefly reviews the research progress on the cytotoxic mechanism of graphene oxide and its derivatives in terms of oxidative stress, physical damage and dysfunction of enzyme activity. This review also discusses effective measures for the mitigation of cytotoxicity in order to provide helpful evidence for occupational health risk and biological safety assessment of graphene nanomaterials in China.
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