Electrospinning for drug delivery applications: A review

Area of Science:

• Materials Science
• Pharmaceutical Sciences
• Biotechnology

Background:

• Drug delivery devices are crucial for maximizing therapeutic efficacy and minimizing adverse effects.
• Electrospun nanofibers are gaining attention for their biocompatibility and flexibility in drug formulations.
• Incorporating active principles into nanofibrous meshes enables efficient in situ drug delivery.

Purpose of the Study:

• To review the principles and applications of electrospinning for drug delivery.
• To provide an overview of recent literature on electrospun nanofibers in pharmaceuticals.
• To highlight the potential of electrospinning for personalized medicine.

Main Methods:

• Review of scientific literature on electrospinning techniques and applications.
• Analysis of studies incorporating active principles into nanofibrous meshes.
• Discussion of the flexibility and tunability of the electrospinning process.

Main Results:

• Electrospinning allows for the creation of nanofibrous meshes with tunable properties.
• Nanofibrous meshes facilitate efficient in situ delivery of various drugs.
• The technique offers broad flexibility and endless combinations for drug formulation.

Conclusions:

• Electrospun nanofibers represent a promising platform for advanced drug delivery systems.
• The adaptability of electrospinning supports a wide range of pharmaceutical applications.
• This technology is poised to be a key component in the future of personalized medicine.