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Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
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Next-Generation Sequencing Is More Efficient at Detecting Mosaic Embryos and Improving Pregnancy Outcomes than

Min Xiao1, Cai-Xia Lei2, Yan-Ping Xi2

  • 1Shanghai Ji Ai Genetics and In Vitro Fertilization Institute, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China; Genetics Center of Obstetrics and Gynecology of Fudan University, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

The Journal of Molecular Diagnostics : JMD
|March 30, 2021
PubMed
Summary

Next-generation sequencing (NGS) preimplantation genetic testing (PGT) detects more chromosomal mosaicism than single-nucleotide polymorphism (SNP) array PGT. This improved detection may lead to better pregnancy outcomes in in vitro fertilization cycles.

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