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Updated: Nov 11, 2025

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18F-FDG PET/CT in Infective Endocarditis on Papillary Muscles: A Case Report
1From the Department of Molecular Imaging, Qingdao Central Hospital, Qingdao University, Qingdao, Shandong, People's Republic of China.
Abstract:
Infective endocarditis is a serious, potentially life-threatening condition. The valve leaflets and annulus are the most commonly affected sites, but involvement of the papillary muscles is extremely rare. We present the case of a 69-year-old woman who had infective endocarditis only involving the papillary muscle on 18F-FDG PET/CT.
Insights
Infective endocarditis typically affects heart valves, but this case highlights a rare instance of infection isolated to the papillary muscle. 18F-FDG PET/CT imaging was crucial in diagnosing this unusual presentation.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Infective endocarditis (IE) is a severe infection of the heart's inner lining, usually affecting the valves.
- Papillary muscle involvement in IE is exceptionally uncommon, posing diagnostic challenges.
Observation:
- A 69-year-old woman presented with symptoms suggestive of endocarditis.
- Imaging revealed the infection was exclusively localized to a papillary muscle.
Findings:
- The case demonstrates infective endocarditis solely involving the papillary muscle.
- 18F-FDG PET/CT successfully identified the rare site of infection.
Implications:
- This case expands the known spectrum of infective endocarditis manifestations.
- Highlights the utility of advanced imaging like 18F-FDG PET/CT in diagnosing rare cardiac infections.
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