Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Circumscribed dermal melanoses. Classification and histologic features.

Y Hori1, O Takayama

  • 1Dermatology, Kyushu University Faculty of Medicine, Fukuoka, Japan.

Dermatologic Clinics
|April 1, 1988
PubMed
Summary

Dermal melanosis involves melanin deposition in the skin, presenting as congenital or acquired conditions. Distinguishing between melanocyte presence and free melanin is key for effective treatment of these pigmentary disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Third-harmonic generation of ultraviolet light in silicon nitride metasurface: a numerical study of pulse duration dependence.

Optics express·2025
Same author

Multicenter prospective trial of total gastrectomy versus proximal gastrectomy for upper third cT1 gastric cancer.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·2020
Same author

Photonic surface waves on metamaterial interfaces.

Journal of physics. Condensed matter : an Institute of Physics journal·2017
Same author

High-Quality Ultrathin Gold Layers with an APTMS Adhesion for Optimal Performance of Surface Plasmon Polariton-Based Devices.

ACS applied materials & interfaces·2017
Same author

Highly doped InP as a low loss plasmonic material for mid-IR region.

Optics express·2016
Same author

Molecular Biomarker Study in a Randomised Phase III Trial of Irinotecan Plus S-1 versus S-1 for Advanced Gastric Cancer (GC0301/TOP-002).

Clinical oncology (Royal College of Radiologists (Great Britain))·2016

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Dermal melanosis results from melanin deposition in melanophages, free in the dermis, or within dermal melanocytes.
  • These pigmentary conditions can be congenital or acquired, sometimes exhibiting nevoid patterns.
  • Associated conditions include nevus of Ota-like lesions with progressive systemic sclerosis, macular amyloidosis, and friction melanosis.

Purpose of the Study:

  • To differentiate between dermal melanoses caused by dermal melanocytes versus free melanin in the dermis.
  • To highlight the clinical similarities and diagnostic challenges of various dermal melanoses.
  • To review treatment options for circumscribed dermal melanoses.

Main Methods:

  • Clinical observation and histopathological examination are crucial for diagnosis.

Related Experiment Videos

  • Differentiating between melanocyte presence and free melanin is a key diagnostic consideration.
  • Review of literature for associated conditions and treatment modalities.

    • Main Results:

    • Dermal melanoses present diverse etiologies, including congenital, acquired, and nevoid forms.
    • Clinical presentation can be similar despite different underlying mechanisms (melanocytes vs. free melanin).
    • Specific associations noted, such as nevus of Ota-like lesions with systemic sclerosis.

    Conclusions:

    • Accurate differentiation of dermal melanosis causes is essential for appropriate management.
    • While treatments like cryotherapy and dermabrasion exist, distinguishing the precise cause is paramount.
    • Further research may elucidate specific treatment pathways based on etiology.