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Chromosome sublocalization of a cDNA for human DNA polymerase-beta to 8p11----p12
L A Cannizzaro1, F J Bollum, K Huebner
1Genetics and Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Cytogenetics and Cell Genetics
|January 1, 1988
Abstract:
We have localized a cDNA fragment that codes for human DNA polymerase-beta. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA library in lambda gt 11 for expression of fused beta-galactosidase-human DNA polymerase-beta proteins. We have mapped this human polymerase-beta gene to the short arm of chromosome 8 in the subregion 8p11----p12.