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Massive striatal dopamine release in acute cerebral ischemia in rats
H Yao1, S Sadoshima, T Ishitsuka
1The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Experientia
|June 15, 1988
Abstract:
Extracellular dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and cerebral blood flow were simultaneously determined using in vivo brain dialysis and a hydrogen clearance method in the striatum of spontaneously hypertensive rats during ischemia and after recirculation. Massive striatal dopamine release was demonstrated in acutely induced ischemic brain.