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Updated: Nov 11, 2025

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10
Published on: November 19, 2016
Source-specific contributions of particulate matter to asthma-related pediatric emergency department utilization
Mohammad Alfrad Nobel Bhuiyan1,2,3, Patrick Ryan2,4, Farzan Oroumyeh5
1Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 USA.
Abstract:
Ambient particulate matter smaller than 2.5 μm (PM2.5) is associated with different chronic diseases. It is crucial to identify the sources of ambient particulate matter to reduce the impact on health. Still, only a few studies have been linked with specific ambient particulate matter sources. In this study, we estimated the contributions of sources of PM2.5 and examined their association with daily asthma hospital utilization in Cincinnati, Ohio, USA. We used a model-based clustering method to group days with similar source-specific contributions into six distinct clusters. Specifically, elevated PM2.5 concentrations occurring on days characterized by low coal combustion contributions showed a significantly reduced risk of hospital utilization for asthma (rate ratio: 0.86, 95% CI: [0.77, 0.95]) compared to other clusters. Reducing coal combustion contribution to PM2.5 levels could be an effective intervention for lowering asthma-related hospital utilization.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s13755-021-00141-z.
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