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Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Published on: January 9, 2019
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Chordoid Glioma With Dot-Like Immunoreactivity for Synaptophysin
Ashley Rose Scholl1, Layla Nasr2, Cesar A Serrano3
1Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University, Morgantown, USA.
Cureus
|March 31, 2021
Summary
This study highlights a rare chordoid glioma case with atypical MRI findings and unique synaptophysin staining. Pathologists and radiologists should consider unusual presentations of these third ventricle tumors.
Area of Science:
- Neuropathology
- Neuro-oncology
- Radiology
Background:
- Chordoid gliomas are rare tumors typically found near the third ventricle.
- They commonly affect individuals around 40 years old, presenting with headaches and visual disturbances.
- Standard imaging shows contrast enhancement, and immunohistochemistry is positive for glial fibrillary acidic protein (GFAP).
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