The Mosan Study Group of pigmented neoplasms
1Department of Dermatology, CHU de Bavière, University of Liège, Belgium.
Summary
Malignant melanoma incidence is rising, particularly in women, excluding lentigo maligna. Melanomas developing from moles are rare, indicating a need for further epidemiological research.
Area of Science:
- Dermatopathology
- Epidemiology
- Oncology
Background:
- Malignant melanomas and their precursors pose a significant public health concern.
- Understanding the epidemiology and histological characteristics is crucial for effective management.
Purpose of the Study:
- To investigate the epidemiology and histological nature of primary cutaneous malignant melanomas and their precursors.
- To analyze trends in melanoma incidence over three decades in a specific Belgian region.
Main Methods:
- Data collection by the Mosan Study Group of Pigmented Neoplasms, involving 9 dermatopathologists and 9 laboratories.
- Analysis of epidemiological and histological information on malignant melanomas.
Main Results:
- A consistent increase in primary cutaneous malignant melanomas (excluding lentigo maligna) over the past 30 years.
- Women are twice as likely to be affected compared to men.
- Malignant melanomas arising from preexisting melanocytic nevi are infrequent.
Conclusions:
- The incidence of malignant melanoma, excluding lentigo maligna, is increasing.
- There is a notable gender disparity in melanoma prevalence.
- Further research into the etiology of melanomas developing on nevi is warranted.


