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Long covid: cross sectional study
Manuel Antonio Prieto1, Omar Prieto2, Horacio Matias Castro3
1Central de Emergencias de Adultos. Hospital Italiano de San Justo Agustín Rocca, Buenos Aires, Argentina.. manuel.prieto@hospitalitaliano.org.ar.
Insights
More than half of patients experience persistent symptoms after Coronavirus disease 2019 (COVID-19). Female sex, obesity, middle age, and hospitalization are linked to ongoing COVID-19 symptoms, necessitating medical follow-up.
Area of Science:
- Medical research
- Public health
Background:
- Coronavirus disease 2019 (COVID-19) remains a significant global health concern.
- A substantial percentage of patients continue to experience symptoms weeks after the initial diagnosis.
- Understanding long-term symptom persistence is crucial for patient management and healthcare planning.
Purpose of the Study:
- To investigate the prevalence of persistent symptoms following COVID-19.
- To identify factors associated with the continuation of symptoms post-acute infection.
- To explore patients' perceptions regarding their recovery and disease experience.
Main Methods:
- A cross-sectional study was conducted with 85 COVID-19 patients.
- Participants attended outpatient consultations more than three weeks after disease onset.
- Data collected included demographics, symptom status, and patient perceptions.
Main Results:
- Over half (52%) of patients reported persistent symptoms beyond three weeks post-COVID-19.
- Fatigue (49%) and cough (33%) were the most common lingering symptoms.
- Factors associated with symptom persistence included female sex, obesity, age (35-55 years), and initial hospitalization.
Conclusions:
- Persistent symptoms are common after COVID-19, highlighting the need for ongoing medical attention.
- Specific demographic and clinical factors are associated with prolonged symptom duration.
- While symptoms typically resolve over time, monitoring is essential for affected individuals.
Introduction:
Coronavirus disease 2019 (COVID-19) is a public health problem worldwide. After 3 weeks of the onset of the disease, between 10-87% of patients persist with symptoms. The objective of the study was to evaluate the persistence of symptoms in patients with COVID-19, the associated factors, and to explore the patients' perception of the disease.
Materials And Methods:
We conducted a cross-sectional study that included 85 patients with a confirmed diagnosis of COVID-19, who attended on an outpatient basis after the acute phase (> 3 weeks) of the disease.
Results:
The median time from diagnosis to outpatient consultation was 53 days (interquartile range 31-65). Most (86%) had mild disease, 45% were women and the mean age was 43 years (standard deviation of 13). After the acute phase of the disease 52% (95% CI 41-63%) of the patients persisted with symptoms. The most frequently persistent symptoms were fatigue (49%) and cough (33%). Nineteen percent had insomnia and sixteen percent had anxiety. Female sex, obesity, age between 35-55 years, and initial hospitalization were associated with the persistence of symptoms. Twenty percent of the patients stopped following the prevention recommendations because they believed they were immunized.
Conclusion:
More than half of the patients persisted with symptoms 3 weeks after the COVID-19 diagnosis, so medical follow-up is important. Female sex, obesity, age 35-55 years, and initial hospitalization were associated factors. The symptoms usually resolved over time.
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