Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized...

Area of Science:

• Anesthesiology
• Medical Devices
• Pharmacoeconomics

Background:

• General anesthesia typically uses a fresh gas flow (FGF) of at least 0.5 L/min.
• Automated gas delivery devices are designed to minimize volatile anesthetic consumption by controlling gas flow.
• This study investigates desflurane use with automated versus conventional low-flow anesthesia systems.

Purpose of the Study:

• To compare desflurane consumption between automated gas control and conventional low-flow anesthesia.
• To evaluate desflurane use in Flow-I and Aisys anesthesia machines.
• To compare the efficacy of two different automated gas delivery devices.

Main Methods:

• 160 patients undergoing robot-assisted laparoscopic surgery were divided into four groups.
• Groups included Flow-I with automated or conventional low-flow (1 L/min) and Aisys with end-tidal gas control or conventional low-flow.
• Anesthesia was maintained at a minimum alveolar concentration (MAC) of 0.7-0.8, with desflurane consumption recorded at 9, 30, and 60 minutes.

Main Results:

• Automated systems reduced desflurane consumption by 60 minutes: Aisys from 25.8 to 15.2 mL (P < .001) and Flow-I from 22.1 to 16.8 mL (P < .001) compared to conventional low flow.
• Aisys end-tidal control achieved target MAC and stable FGF faster than Flow-I automated gas control.
• Both automated gas delivery devices demonstrated reliability in clinical use.

Conclusions:

• Automated gas delivery devices significantly decrease desflurane consumption compared to conventional low-flow anesthesia.
• The study confirms the effectiveness and reliability of automated systems in reducing anesthetic agent usage.
• Automated anesthesia delivery systems offer a viable method for optimizing volatile anesthetic management.