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Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
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HIV Infection in Adults: Initial Management
Ronald Goldschmidt1, Carolyn Chu1
1University of California-San Francisco and Zuckerberg San Francisco General Hospital, San Francisco, CA, USA.
American Family Physician
|March 31, 2021
Summary
Early initiation of antiretroviral therapy (ART) is crucial for managing HIV, improving patient health, and preventing transmission. Continuous treatment ensures viral suppression and better long-term outcomes for people with HIV.
Area of Science:
- Public Health
- Infectious Diseases
- Family Medicine
Background:
- The HIV epidemic remains a significant public health concern, with ongoing transmissions despite available treatments.
- About half of individuals with HIV are not on suppressive antiretroviral therapy (ART).
Purpose of the Study:
- To highlight the importance of early and continuous ART for managing HIV.
- To outline key considerations for initiating and managing HIV treatment.
Main Methods:
- Review of current national treatment guidelines for HIV.
- Emphasis on comprehensive laboratory evaluation and psychosocial support.
Main Results:
- Early ART initiation leads to durable virologic suppression and immune restoration.
- ART can be started immediately after diagnosis, prior to resistance testing.
Conclusions:
- Optimal HIV management involves early, continuous ART, guided by individual patient factors.
- Addressing psychosocial barriers is essential for treatment adherence and reducing transmissions.
- Family physicians play a vital role in long-term HIV care and prevention.
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