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    Area of Science:

    • Biomedical Engineering
    • Rehabilitation Technology
    • Wearable Sensors

    Background:

    • Subject-specific electromyogram (EMG)-torque models show poor performance on new subjects or re-tests.
    • Improving model generalization is critical for practical applications of EMG-based control.

    Purpose of the Study:

    • To investigate data acquisition and utilization strategies for enhancing cross-subject EMG-torque model performance.
    • To propose and evaluate a novel unsupervised data weighting method for model calibration.

    Main Methods:

    • Analyzed data from 65 subjects to determine the impact of training set diversity versus size.
    • Developed a correlation-based data weighting (COR-W) method to assess domain shift using EMG signals.
    • Applied weighted least squares for model calibration using COR-W assigned data weights.

    Main Results:

    • Training set data diversity (number of subjects) is more critical than data size for model performance.
    • The COR-W method achieved a low root mean square error (9.29% MVC) in cross-subject evaluation.
    • Significant performance improvements were observed compared to uncalibrated models.

    Conclusions:

    • Data acquisition diversity and the COR-W utilization strategy effectively improve EMG-torque model generalization.
    • The COR-W method offers an unsupervised approach for calibrating EMG-torque models in cross-subject scenarios.