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Related Experiment Video

Updated: Nov 10, 2025

Right Hemihepatectomy by Suprahilar Intrahepatic Transection of the Right Hemipedicle using a Vascular Stapler
03:45

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Rationality and necessity of vascular stapler application during liver resection (Review).

Er-Lei Zhang1, Zhi-Yong Huang1, Xiao-Ping Chen1

  • 1Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China.

Experimental and Therapeutic Medicine
|April 1, 2021
PubMed
Summary
This summary is machine-generated.

Vascular staplers in liver resection for hepatocellular carcinoma (HCC) may increase costs without improving outcomes. Routine use is not recommended, favoring stapling in laparoscopic procedures and suturing in open liver resection.

Keywords:
liver resectionnecessityrationalityvascular staplervessel transection

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Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Gastroenterology

Background:

  • Liver resection (LR) is a primary treatment for hepatocellular carcinoma (HCC).
  • Minimizing blood loss and complications during LR is crucial for patient outcomes.
  • Vascular staplers are increasingly used for vessel transection in LR, but their efficacy and necessity are debated.

Purpose of the Study:

  • To review the rationale and necessity of using vascular staplers for vessel transection during liver surgery.
  • To evaluate the benefits and drawbacks of vascular staplers compared to traditional methods in LR for HCC.

Main Methods:

  • Review of existing literature on vascular stapler use in liver resection.
  • Comparison of stapling techniques versus clamp-crushing and suturing ligation methods.
  • Analysis of surgical outcomes, blood loss, operative time, and financial implications.

Main Results:

  • Vascular staplers may not significantly reduce blood loss or improve short- and long-term outcomes compared to clamp-crushing.
  • Stapling can lead to smaller surgical margins.
  • The use of vascular staplers increases the financial burden of liver resection.

Conclusions:

  • Vascular staplers should not be routinely used in all liver resections for HCC.
  • Stapling transection may be rationally applied during laparoscopic LR.
  • Suturing ligation remains the recommended routine method for open LR.