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Related Concept Videos

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

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Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
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Related Experiment Video

Updated: Nov 10, 2025

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
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Probiotics in Cancer.

Ke Lu1, Shanwu Dong2,3, Xiaoyan Wu1

  • 1Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Frontiers in Oncology
|April 1, 2021
PubMed
Summary
This summary is machine-generated.

Probiotics offer health benefits but can cause rare adverse reactions. Their use in cancer patients requires further investigation to understand benefits and risks.

Keywords:
cancerclinical trialsprobioticssafetytreatment

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Area of Science:

  • Microbiology
  • Immunology
  • Oncology

Background:

  • Probiotics are widely consumed for health, with demonstrated benefits for immune and intestinal health.
  • Despite general safety, rare adverse reactions to probiotics can occur.
  • Clinical trial results for probiotics are often contradictory, especially in specific populations.

Purpose of the Study:

  • To review the interactions between probiotics and the host.
  • To summarize current knowledge on the advantages and disadvantages of probiotic use in cancer patients.
  • To investigate the potential of probiotics in cancer management and mitigating treatment side effects.

Main Methods:

  • Literature review of clinical trials and scientific studies on probiotics.
  • Analysis of host-probiotic interactions.
  • Evaluation of evidence for probiotic efficacy and safety in oncology.

Main Results:

  • Probiotics modulate the immune system and gut microbiota.
  • Evidence for probiotic benefits in cancer patients is mixed and requires more research.
  • Potential risks and benefits of probiotics in cancer care need careful consideration.

Conclusions:

  • Probiotics have a complex role in human health, with variable outcomes.
  • Further research is crucial to establish the safety and efficacy of probiotics in cancer patients.
  • Personalized approaches may be necessary for probiotic interventions in oncology.