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Reflex sympathetic dystrophy and cigarette smoking.

H S An1, K B Hawthorne, W T Jackson

  • 1Department of Orthopaedic Surgery, Medical College of Ohio, Toledo 43699.

The Journal of Hand Surgery
|May 1, 1988
PubMed
Summary
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Cigarette smoking is strongly linked to reflex sympathetic dystrophy (RSD), with 68% of patients being smokers compared to 37% of controls. This suggests smoking may play a role in RSD development.

Area of Science:

  • Neurology
  • Epidemiology
  • Vascular Medicine

Background:

  • The exact cause of reflex sympathetic dystrophy (RSD) is unknown.
  • Sympathetic nerve hyperactivity and vasospasm are suspected contributors to RSD pathogenesis.
  • RSD is a complex condition affecting the nervous and vascular systems.

Purpose of the Study:

  • To investigate potential risk factors and epidemiological characteristics of reflex sympathetic dystrophy (RSD).
  • To explore the association between cigarette smoking and the incidence of RSD.
  • To identify factors that may contribute to the development of RSD.

Main Methods:

  • A retrospective epidemiological study was conducted.
  • Data were collected from 53 in-patients diagnosed with RSD between 1978 and 1985.

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  • Patient data were compared with hospitalized control groups.

    • Main Results:

    • Cigarette smoking was significantly more prevalent in RSD patients (68%) compared to controls (37%) (p < 0.0001).
    • A history of trauma or surgery was reported in 87% of RSD patients.
    • Comorbidities were present in 38% of the patients studied.

    Conclusions:

    • Cigarette smoking shows a statistically significant link to reflex sympathetic dystrophy (RSD).
    • Smoking may contribute to RSD pathogenesis through mechanisms like enhanced sympathetic activity or vasoconstriction.
    • Further research is needed to elucidate the precise role of smoking in RSD.