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Overcoming Barriers to Clinical Trials Cooperation: The Breast International Group Example
Martine J Piccart-Gebhart1, Theodora Goulioti2, Carolyn Straehle2
1Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Summary
Clinical trial cooperation is essential for academic research and patient needs. The Breast International Group has addressed challenges in network trust, industry collaboration, patient involvement, and funding for noncommercial research.
Area of Science:
- Oncology
- Clinical Research
- Translational Medicine
Background:
- Precision medicine in oncology necessitates robust clinical trial cooperation.
- Academic research must remain patient-centered amidst competitive drug development.
- The Breast International Group (BIG) has operated for 21 years, supporting global breast cancer research.
Purpose of the Study:
- To outline the challenges faced by a global breast cancer clinical trials cooperative group.
- To describe strategies employed by the Breast International Group to overcome these challenges.
- To provide insights for empowering future clinical investigators in cooperative research.
Main Methods:
- The Breast International Group's 21-year experience provides a case study.
- Analysis of challenges encountered in network management, academia-industry interface, patient engagement, and funding.
- Description of implemented solutions and approaches.
Main Results:
- BIG has navigated challenges in maintaining network trust and motivation.
- Improvements have been made in the interface between academic research and the pharmaceutical industry.
- Strategies for enhancing patient involvement and trust in clinical trials have been developed.
- Fundraising efforts for noncommercial research have been undertaken.
Conclusions:
- Effective clinical trial cooperation is crucial for advancing cancer research and patient care.
- Addressing network, industry, patient, and funding challenges is key to successful cooperative research.
- The Breast International Group's experience offers valuable lessons for the future of clinical investigation.
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