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[Spermatozoa karyotyping and meiotic segregation: a study of 4 reciprocal translocations]
F Pellestor1, B Sele, P Jalbert
1Laboratoire de Cytogénétique et de Biologie de la Reproduction, Faculté de Médecine de Grenoble, France.
Journal De Genetique Humaine
|January 1, 1988
Abstract:
Sperm cytogenetics was carried out using technique of in vitro heterospecific human-hamster fertilization. Sperm of 4 men heterozygous from 4 reciprocal translocations (t(4; 17), t(5; 13), t(6; 7) and t(9; 18] was studied. Segregations were various but a majority of unbalanced complements resulting from adjacent 1 segregations was observed. This prevalence was stronger when the pachytene diagram predisposed the translocation to this mode of imbalance at term.