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Published on: August 20, 2021
Draft Genome Sequence of a Multidrug-Resistant Klebsiella pneumoniae Isolate from a Prosthetic Joint Infection
Hosoon Choi1, Chetan Jinadatha2,3, Piyali Chatterjee1
1Research Service, Central Texas Veterans Health Care System, Temple, Texas, USA.
Abstract:
Extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae strain 9120005127 was isolated from a wound infection. We describe the draft genome sequence and antibiotic susceptibility of this strain.
Insights
A wound infection was caused by an extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae strain. This study details the genome sequence and antibiotic susceptibility of this specific ESBL-producing Klebsiella pneumoniae strain.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Extended-spectrum β-lactamase (ESBL)-producing bacteria are a growing public health concern.
- Klebsiella pneumoniae is a common cause of hospital-acquired infections, including wound infections.
- Antimicrobial resistance in K. pneumoniae complicates treatment options.
Purpose of the Study:
- To report the draft genome sequence of an ESBL-producing Klebsiella pneumoniae strain (9120005127) isolated from a wound infection.
- To characterize the antibiotic susceptibility profile of this specific strain.
Main Methods:
- Whole-genome sequencing was performed on the isolated Klebsiella pneumoniae strain.
- Antibiotic susceptibility testing was conducted using standard microbiological methods.
Main Results:
- The draft genome sequence of Klebsiella pneumoniae strain 9120005127 was successfully generated.
- The strain exhibited resistance to several key antibiotic classes, consistent with ESBL production.
Conclusions:
- The genomic data provides a foundation for understanding the genetic basis of antimicrobial resistance in this strain.
- This information is crucial for guiding treatment strategies for infections caused by this or similar ESBL-producing Klebsiella pneumoniae isolates.
