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Aggressive lesion in osseous sarcoidosis
R S Lesser1, S Dadparvar, A A Weiss
1Department of Orthopedic Surgery, Hahnemann University School of Medicine, Philadelphia, PA.
The Journal of Rheumatology
|March 1, 1988
Summary
This study details an aggressive bone lesion in a patient with sarcoidosis, characterized by a unique "sunburst/hair-on-end" periosteal reaction. The findings highlight an unusual presentation of osseous sarcoid, prompting a review of similar cases.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Sarcoidosis is a multisystem inflammatory disease.
- Osseous sarcoidosis, while rare, can present with diverse bone lesions.
- Aggressive lytic bone lesions require careful differential diagnosis.
Observation:
- An unusual aggressive lytic bone lesion was identified.
- The lesion exhibited a distinct "sunburst/hair-on-end" periosteal reaction on imaging.
- The patient had surgically confirmed osseous sarcoidosis.
Findings:
- The described lesion represents an atypical manifestation of osseous sarcoidosis.
- The "sunburst/hair-on-end" periosteal reaction is not a typical finding in osseous sarcoid.
- Literature review supports the rarity of this presentation.
Implications:
- This case expands the understanding of the radiographic spectrum of osseous sarcoidosis.
- Highlights the importance of considering sarcoidosis in the differential diagnosis of aggressive bone lesions with unusual periosteal reactions.
- Suggests further investigation into the pathogenesis of varied osseous sarcoid presentations.