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Capturing pathogenic immune cells before they home to brain
1Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA.
Abstract:
In this issue, Kaufmann and colleagues1 describe a population of immune cells that home to brain in multiple sclerosis (MS). Using an approved therapeutic, targeting α4β1integrin, they demonstrated how to trap these cells in blood, opening the possibility for their elimination before they cross into brain.
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